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Fatty Acids Enhance the Maturation of Cardiomyocytes Derived from Human Pluripotent Stem Cells

Although human pluripotent stem cell-derived cardiomyocytes (hPSC-CMs) have emerged as a novel platform for heart regeneration, disease modeling, and drug screening, their immaturity significantly hinders their application. A hallmark of postnatal cardiomyocyte maturation is the metabolic substrate...

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Detalles Bibliográficos
Autores principales: Yang, Xiulan, Rodriguez, Marita L., Leonard, Andrea, Sun, Lihua, Fischer, Karin A., Wang, Yuliang, Ritterhoff, Julia, Zhao, Limei, Kolwicz, Stephen C., Pabon, Lil, Reinecke, Hans, Sniadecki, Nathan J., Tian, Rong, Ruohola-Baker, Hannele, Xu, Haodong, Murry, Charles E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6829750/
https://www.ncbi.nlm.nih.gov/pubmed/31564645
http://dx.doi.org/10.1016/j.stemcr.2019.08.013