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Single-Cell RNA Sequencing of hESC-Derived 3D Retinal Organoids Reveals Novel Genes Regulating RPC Commitment in Early Human Retinogenesis

The development of the mammalian retina is a complicated process involving the generation of distinct types of neurons from retinal progenitor cells (RPCs) in a spatiotemporal-specific manner. The progression of RPCs during retinogenesis includes RPC proliferation, cell-fate commitment, and specific...

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Detalles Bibliográficos
Autores principales: Mao, Xiying, An, Qin, Xi, Huiyu, Yang, Xian-Jie, Zhang, Xiangmei, Yuan, Songtao, Wang, Jinmei, Hu, Youjin, Liu, Qinghuai, Fan, Guoping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6829752/
https://www.ncbi.nlm.nih.gov/pubmed/31543471
http://dx.doi.org/10.1016/j.stemcr.2019.08.012