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Single-Cell RNA Sequencing of hESC-Derived 3D Retinal Organoids Reveals Novel Genes Regulating RPC Commitment in Early Human Retinogenesis

The development of the mammalian retina is a complicated process involving the generation of distinct types of neurons from retinal progenitor cells (RPCs) in a spatiotemporal-specific manner. The progression of RPCs during retinogenesis includes RPC proliferation, cell-fate commitment, and specific...

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Detalles Bibliográficos
Autores principales:	Mao, Xiying, An, Qin, Xi, Huiyu, Yang, Xian-Jie, Zhang, Xiangmei, Yuan, Songtao, Wang, Jinmei, Hu, Youjin, Liu, Qinghuai, Fan, Guoping
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6829752/ https://www.ncbi.nlm.nih.gov/pubmed/31543471 http://dx.doi.org/10.1016/j.stemcr.2019.08.012

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