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A Chemically Defined Feeder-free System for the Establishment and Maintenance of the Human Naive Pluripotent State

The distinct states of pluripotency in the pre- and post-implantation embryo can be captured in vitro as naive and primed pluripotent stem cell cultures, respectively. The study and application of the naive state remains hampered, particularly in humans, partially due to current culture protocols re...

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Detalles Bibliográficos
Autores principales: Szczerbinska, Iwona, Gonzales, Kevin Andrew Uy, Cukuroglu, Engin, Ramli, Muhammad Nadzim Bin, Lee, Bertha Pei Ge, Tan, Cheng Peow, Wong, Cheng Kit, Rancati, Giulia Irene, Liang, Hongqing, Göke, Jonathan, Ng, Huck-Hui, Chan, Yun-Shen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6829768/
https://www.ncbi.nlm.nih.gov/pubmed/31522974
http://dx.doi.org/10.1016/j.stemcr.2019.08.005