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A Chemically Defined Feeder-free System for the Establishment and Maintenance of the Human Naive Pluripotent State
The distinct states of pluripotency in the pre- and post-implantation embryo can be captured in vitro as naive and primed pluripotent stem cell cultures, respectively. The study and application of the naive state remains hampered, particularly in humans, partially due to current culture protocols re...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6829768/ https://www.ncbi.nlm.nih.gov/pubmed/31522974 http://dx.doi.org/10.1016/j.stemcr.2019.08.005 |