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Late Onset of Estrogen Therapy Impairs Carotid Function of Senescent Females in Association with Altered Prostanoid Balance and Upregulation of the Variant ERα36

Recent analysis of clinical trials on estrogen therapy proposes the existence of a therapeutic window of opportunity for the cardiovascular benefits of estrogens, which depend on women’s age and the onset of therapy initiation. In this study, we aimed to determine how vascular senescence and the ons...

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Detalles Bibliográficos
Autores principales: Januário Costa, Tiago, Jiménez-Altayó, Francesc, Echem, Cinthya, Akamine, Eliana Hiromi, Tostes, Rita, Vila, Elisabet, Dantas, Ana Paula, Catelli de Carvalho, Maria Helena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6829869/
https://www.ncbi.nlm.nih.gov/pubmed/31597326
http://dx.doi.org/10.3390/cells8101217