A Machine Learning-Based Prediction Platform for P-Glycoprotein Modulators and Its Validation by Molecular Docking

P-glycoprotein (P-gp) is an important determinant of multidrug resistance (MDR) because its overexpression is associated with increased efflux of various established chemotherapy drugs in many clinically resistant and refractory tumors. This leads to insufficient therapeutic targeting of tumor popul...

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Detalles Bibliográficos
Autores principales: Kadioglu, Onat, Efferth, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6829872/
https://www.ncbi.nlm.nih.gov/pubmed/31640190
http://dx.doi.org/10.3390/cells8101286

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6829872/
https://www.ncbi.nlm.nih.gov/pubmed/31640190
http://dx.doi.org/10.3390/cells8101286

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