Below the Surface: IGF-1R Therapeutic Targeting and Its Endocytic Journey

Ligand-activated plasma membrane receptors follow pathways of endocytosis through the endosomal sorting apparatus. Receptors cluster in clathrin-coated pits that bud inwards and enter the cell as clathrin-coated vesicles. These vesicles travel through the acidic endosome whereby receptors and ligand...

Descripción completa

Detalles Bibliográficos
Autores principales: Crudden, Caitrin, Song, Dawei, Cismas, Sonia, Trocmé, Eric, Pasca, Sylvya, Calin, George A., Girnita, Ada, Girnita, Leonard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6829878/
https://www.ncbi.nlm.nih.gov/pubmed/31600876
http://dx.doi.org/10.3390/cells8101223

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6829878/
https://www.ncbi.nlm.nih.gov/pubmed/31600876
http://dx.doi.org/10.3390/cells8101223

Ejemplares similares