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Below the Surface: IGF-1R Therapeutic Targeting and Its Endocytic Journey

Ligand-activated plasma membrane receptors follow pathways of endocytosis through the endosomal sorting apparatus. Receptors cluster in clathrin-coated pits that bud inwards and enter the cell as clathrin-coated vesicles. These vesicles travel through the acidic endosome whereby receptors and ligand...

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Detalles Bibliográficos
Autores principales:	Crudden, Caitrin, Song, Dawei, Cismas, Sonia, Trocmé, Eric, Pasca, Sylvya, Calin, George A., Girnita, Ada, Girnita, Leonard
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2019
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6829878/ https://www.ncbi.nlm.nih.gov/pubmed/31600876 http://dx.doi.org/10.3390/cells8101223

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