Inhibition of Non-Small Cell Lung Cancer Cells by Oxy210, an Oxysterol-Derivative that Antagonizes TGFβ and Hedgehog Signaling

Non-Small Cell Lung Cancer (NSCLC) is a common malignancy and leading cause of death by cancer. Metastasis and drug resistance are serious clinical problems encountered in NSCLC therapy. Aberrant activation of the Transforming Growth Factor beta (TGFβ) and Hedgehog (Hh) signal transduction cascades...

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Detalles Bibliográficos
Autores principales: Stappenbeck, Frank, Wang, Feng, Tang, Liu-Ya, Zhang, Ying E., Parhami, Farhad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6829886/
https://www.ncbi.nlm.nih.gov/pubmed/31652618
http://dx.doi.org/10.3390/cells8101297

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6829886/
https://www.ncbi.nlm.nih.gov/pubmed/31652618
http://dx.doi.org/10.3390/cells8101297

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