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Neurofilament light chain is a promising serum biomarker in spinocerebellar ataxia type 3

BACKGROUND: Spinocerebellar ataxia type 3 (SCA3) is the most common subtype of autosomal dominantly inherited spinocerebellar ataxias (SCAs). No validated blood biomarker is available to assess either disease progression or therapeutic response. Neurofilament light chain (NfL) was recently proposed...

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Detalles Bibliográficos
Autores principales: Li, Quan-Fu, Dong, Yi, Yang, Lu, Xie, Juan-Juan, Ma, Yin, Du, Yi-Chu, Cheng, Hao-Ling, Ni, Wang, Wu, Zhi-Ying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6829913/
https://www.ncbi.nlm.nih.gov/pubmed/31684998
http://dx.doi.org/10.1186/s13024-019-0338-0