Direct conversion of human fibroblast to hepatocytes using a single inducible polycistronic vector

BACKGROUND: Human fibroblasts can be reprogrammed into induced hepatocyte-like cells through the expression of a set of transcription factors. Although the generation of induced hepatocyte-like cells by HNF4A, HNF1A, and FOXA3 expression has proven to be a robust experimental strategy, using multipl...

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Detalles Bibliográficos
Autores principales: Ballester, Maria, Bolonio, Miguel, Santamaria, Ramon, Castell, José V., Ribes-Koninckx, Carmen, Bort, Roque
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6829923/
https://www.ncbi.nlm.nih.gov/pubmed/31685034
http://dx.doi.org/10.1186/s13287-019-1416-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6829923/
https://www.ncbi.nlm.nih.gov/pubmed/31685034
http://dx.doi.org/10.1186/s13287-019-1416-5

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