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Direct conversion of human fibroblast to hepatocytes using a single inducible polycistronic vector

BACKGROUND: Human fibroblasts can be reprogrammed into induced hepatocyte-like cells through the expression of a set of transcription factors. Although the generation of induced hepatocyte-like cells by HNF4A, HNF1A, and FOXA3 expression has proven to be a robust experimental strategy, using multipl...

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Detalles Bibliográficos
Autores principales:	Ballester, Maria, Bolonio, Miguel, Santamaria, Ramon, Castell, José V., Ribes-Koninckx, Carmen, Bort, Roque
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2019
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6829923/ https://www.ncbi.nlm.nih.gov/pubmed/31685034 http://dx.doi.org/10.1186/s13287-019-1416-5

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