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SP600125 enhances C-2-induced cell death by the switch from autophagy to apoptosis in bladder cancer cells
BACKGROUND: A natural compound Jaspine B and its derivative possess potential anti-cancer activities; However, little is known about the underlying mechanism. Here, the role of a new autophagy inducer Jaspine B derivative C-2 in suppressing bladder cancer cells was researched in vitro and in vivo. M...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6829950/ https://www.ncbi.nlm.nih.gov/pubmed/31685029 http://dx.doi.org/10.1186/s13046-019-1467-6 |