SP600125 enhances C-2-induced cell death by the switch from autophagy to apoptosis in bladder cancer cells

BACKGROUND: A natural compound Jaspine B and its derivative possess potential anti-cancer activities; However, little is known about the underlying mechanism. Here, the role of a new autophagy inducer Jaspine B derivative C-2 in suppressing bladder cancer cells was researched in vitro and in vivo. M...

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Detalles Bibliográficos
Autores principales: Yu, Haiyang, Wu, Chun-Li, Wang, Xiangyu, Ban, Qianhong, Quan, Chunhua, Liu, Mengbo, Dong, Hangqi, Li, Jinfeng, Kim, Gi-Young, Choi, Yung Hyun, Wang, Zhenya, Jin, Cheng-Yun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6829950/
https://www.ncbi.nlm.nih.gov/pubmed/31685029
http://dx.doi.org/10.1186/s13046-019-1467-6

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