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The impact of hepatocyte nuclear factor-1α on liver malignancies and cell stemness with metabolic consequences

Hepatocyte nuclear factor-1 alpha (HNF-1α) is a transcription factor expressed predominantly in the liver among other organs. Structurally, it contains POU-homeodomain that binds to DNA and form proteins that help in maintaining cellular homeostasis, controlling metabolism, and differentiating cell...

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Detalles Bibliográficos
Autores principales: Wang, Xue, Hassan, Waseem, Zhao, Jing, Bakht, Sahar, Nie, Yunjuan, Wang, Ying, Pang, Qingfeng, Huang, Zhaohui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6829964/
https://www.ncbi.nlm.nih.gov/pubmed/31685031
http://dx.doi.org/10.1186/s13287-019-1438-z