Cargando…
Evaluation of human primary intestinal monolayers for drug metabolizing capabilities
BACKGROUND: The intestinal epithelium is a major site of drug metabolism in the human body, possessing enterocytes that house brush border enzymes and phase I and II drug metabolizing enzymes (DMEs). The enterocytes are supported by a porous extracellular matrix (ECM) that enables proper cell adhesi...
| Autores principales: | , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2019
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6829970/ https://www.ncbi.nlm.nih.gov/pubmed/31709009 http://dx.doi.org/10.1186/s13036-019-0212-1 |