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Interplay between Metabolites and the Epigenome in Regulating Embryonic and Adult Stem Cell Potency and Maintenance

The environment surrounding stem cells has the ability to elicit profound, heritable epigenetic changes orchestrated by multiple epigenetic mechanisms, which can be modulated by the level of specific metabolites. In this review, we highlight the significance of metabolism in regulating stem cell hom...

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Detalles Bibliográficos
Autores principales: Harvey, Alexandra, Caretti, Giuseppina, Moresi, Viviana, Renzini, Alessandra, Adamo, Sergio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6830055/
https://www.ncbi.nlm.nih.gov/pubmed/31597110
http://dx.doi.org/10.1016/j.stemcr.2019.09.003