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Interplay between Metabolites and the Epigenome in Regulating Embryonic and Adult Stem Cell Potency and Maintenance
The environment surrounding stem cells has the ability to elicit profound, heritable epigenetic changes orchestrated by multiple epigenetic mechanisms, which can be modulated by the level of specific metabolites. In this review, we highlight the significance of metabolism in regulating stem cell hom...
Autores principales: | Harvey, Alexandra, Caretti, Giuseppina, Moresi, Viviana, Renzini, Alessandra, Adamo, Sergio |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6830055/ https://www.ncbi.nlm.nih.gov/pubmed/31597110 http://dx.doi.org/10.1016/j.stemcr.2019.09.003 |
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