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H3K18ac Primes Mesendodermal Differentiation upon Nodal Signaling

Cellular responses to transforming growth factor β (TGF-β) depend on cell context. Here, we explored how TGF-β/nodal signaling crosstalks with the epigenome to promote mesendodermal differentiation. We find that expression of a group of mesendodermal genes depends on both TRIM33 and nodal signaling...

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Detalles Bibliográficos
Autores principales: Luo, Maoguo, Bai, Jianbo, Liu, Bofeng, Yan, Peiqiang, Zuo, Feifei, Sun, Hongyao, Sun, Ye, Xu, Xuanhao, Song, Zhihong, Yang, Yang, Massagué, Joan, Lan, Xun, Lu, Zhi, Chen, Ye-Guang, Deng, Haiteng, Xie, Wei, Xi, Qiaoran
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6830056/
https://www.ncbi.nlm.nih.gov/pubmed/31564646
http://dx.doi.org/10.1016/j.stemcr.2019.08.016