A Diet Induced Maladaptive Increase in Hepatic Mitochondrial DNA Precedes OXPHOS Defects and May Contribute to Non-Alcoholic Fatty Liver Disease

Non-alcoholic fatty liver disease (NAFLD), an increasingly prevalent and underdiagnosed disease, is postulated to be caused by hepatic fat mediated pathological mechanisms. Mitochondrial dysfunction is proposed to be involved, but it is not known whether this is a pathological driver or a consequenc...

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Detalles Bibliográficos
Autores principales: Malik, Afshan N, Simões, Inês C.M., Rosa, Hannah S., Khan, Safa, Karkucinska-Wieckowska, Agnieszka, Wieckowski, Mariusz R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6830072/
https://www.ncbi.nlm.nih.gov/pubmed/31597406
http://dx.doi.org/10.3390/cells8101222

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6830072/
https://www.ncbi.nlm.nih.gov/pubmed/31597406
http://dx.doi.org/10.3390/cells8101222

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