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Capsaicin Targets tNOX (ENOX2) to Inhibit G1 Cyclin/CDK Complex, as Assessed by the Cellular Thermal Shift Assay (CETSA)

Capsaicin (8-methyl-N-vanillyl-6-noneamide), which is an active component in red chili peppers, is used as a chemopreventive agent that shows favorable cytotoxicity against cancer cells. Accumulating evidence indicates that capsaicin preferentially inhibits a tumor-associated NADH oxidase (tNOX, ENO...

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Detalles Bibliográficos
Autores principales: Islam, Atikul, Su, Ally J., Zeng, Zih-Ming, Chueh, Pin Ju, Lin, Ming-Hung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6830080/
https://www.ncbi.nlm.nih.gov/pubmed/31635402
http://dx.doi.org/10.3390/cells8101275