Intrinsically Disordered SRC-3/AIB1 Protein Undergoes Homeostatic Nuclear Extrusion by Nuclear Budding While Ectopic Expression Induces Nucleophagy

SRC-3/AIB1 (Amplified in Breast Cancer-1) is a nuclear receptor coactivator for the estrogen receptor in breast cancer cells. It is also an intrinsically disordered protein when not engaged with transcriptional binding partners and degraded upon transcriptional coactivation. Given the amplified expr...

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Detalles Bibliográficos
Autores principales: Cabrita, Miguel A., Renart, L. Isabel, Lau, Rosanna, Pratt, M. A. Christine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6830083/
https://www.ncbi.nlm.nih.gov/pubmed/31635050
http://dx.doi.org/10.3390/cells8101278

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6830083/
https://www.ncbi.nlm.nih.gov/pubmed/31635050
http://dx.doi.org/10.3390/cells8101278

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