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Vacuolar H(+)-ATPase Subunit V0C Regulates Aerobic Glycolysis of Esophageal Cancer Cells via PKM2 Signaling

The vacuolar H(+)-adenosine triphosphatase (ATPase) subunit V0C (ATP6V0C), a proton-conducting, pore-forming subunit of vacuolar ATPase, maintains pH homeostasis and induces organelle acidification. The intracellular and extracellular pH of cancer cells affects their growth; however, the role of ATP...

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Detalles Bibliográficos
Autores principales: Son, Sung Wook, Chau, Gia Cac, Kim, Seong-Tae, Um, Sung Hee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6830105/
https://www.ncbi.nlm.nih.gov/pubmed/31554233
http://dx.doi.org/10.3390/cells8101137