Cargando…

The E-Cadherin and N-Cadherin Switch in Epithelial-to-Mesenchymal Transition: Signaling, Therapeutic Implications, and Challenges

Epithelial-to-Mesenchymal Transition (EMT) has been shown to be crucial in tumorigenesis where the EMT program enhances metastasis, chemoresistance and tumor stemness. Due to its emerging role as a pivotal driver of tumorigenesis, targeting EMT is of great therapeutic interest in counteracting metas...

Descripción completa

Detalles Bibliográficos
Autores principales: Loh, Chin-Yap, Chai, Jian Yi, Tang, Ting Fang, Wong, Won Fen, Sethi, Gautam, Shanmugam, Muthu Kumaraswamy, Chong, Pei Pei, Looi, Chung Yeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6830116/
https://www.ncbi.nlm.nih.gov/pubmed/31547193
http://dx.doi.org/10.3390/cells8101118