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Vascular endothelial growth factor improves the therapeutic effects of cyclodextrin in Niemann-Pick type C mice
Niemann-Pick type C disease (NP-C) is a fatal neurodegenerative disorder caused by a deficiency in the function of the NPC1 gene. Malfunction of this gene/protein leads to progressive accumulation of unesterified cholesterol and sphingolipids in many organs, including the brain. To date, drugs that...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6830204/ https://www.ncbi.nlm.nih.gov/pubmed/31700700 http://dx.doi.org/10.1080/19768354.2019.1651768 |