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Vascular endothelial growth factor improves the therapeutic effects of cyclodextrin in Niemann-Pick type C mice

Niemann-Pick type C disease (NP-C) is a fatal neurodegenerative disorder caused by a deficiency in the function of the NPC1 gene. Malfunction of this gene/protein leads to progressive accumulation of unesterified cholesterol and sphingolipids in many organs, including the brain. To date, drugs that...

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Detalles Bibliográficos
Autores principales: Jeong, Min Seock, Bae, Jae-sung, Jin, Hee Kyung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6830204/
https://www.ncbi.nlm.nih.gov/pubmed/31700700
http://dx.doi.org/10.1080/19768354.2019.1651768