Cargando…

Crystal structure of the putative cyclase IdmH from the indanomycin nonribosomal peptide synthase/polyketide synthase

Indanomycin is biosynthesized by a hybrid nonribosomal peptide synthase/polyketide synthase (NRPS/PKS) followed by a number of ‘tailoring’ steps to form the two ring systems that are present in the mature product. It had previously been hypothesized that the indane ring of indanomycin was formed by...

Descripción completa

Detalles Bibliográficos
Autores principales: Drulyte, Ieva, Obajdin, Jana, Trinh, Chi H., Kalverda, Arnout P., van der Kamp, Marc W., Hemsworth, Glyn R., Berry, Alan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6830212/
https://www.ncbi.nlm.nih.gov/pubmed/31709067
http://dx.doi.org/10.1107/S2052252519012399