Mutagenesis facilitated crystallization of GLP-1R

The class B family of G-protein-coupled receptors (GPCRs) has long been a paradigm for peptide hormone recognition and signal transduction. One class B GPCR, the glucagon-like peptide-1 receptor (GLP-1R), has been considered as an anti-diabetes drug target and there are several peptidic drugs availa...

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Detalles Bibliográficos
Autores principales: Xu, Yueming, Wang, Yuxia, Wang, Yang, Liu, Kaiwen, Peng, Yao, Yao, Deqiang, Tao, Houchao, Liu, Haiguang, Song, Gaojie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2019
Materias:
Research Letters
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6830218/
https://www.ncbi.nlm.nih.gov/pubmed/31709055
http://dx.doi.org/10.1107/S2052252519013496

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6830218/
https://www.ncbi.nlm.nih.gov/pubmed/31709055
http://dx.doi.org/10.1107/S2052252519013496

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