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B Cell-Based Vaccine Transduced With ESAT6-Expressing Vaccinia Virus and Presenting α-Galactosylceramide Is a Novel Vaccine Candidate Against ESAT6-Expressing Mycobacterial Diseases

Early secretory antigenic target-6 (ESAT6) is a potent immunogenic antigen expressed in Mycobacterium tuberculosis as well as in some non-tuberculous mycobacteria (NTM), such as M. kansasii. M. kansasii is one of the most clinically relevant species of NTM that causes mycobacterial lung disease, whi...

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Detalles Bibliográficos
Autores principales: Kwon, Bo-Eun, Ahn, Jae-Hee, Park, Eun-Kyoung, Jeong, Hyunjin, Lee, Hyo-Ji, Jung, Yu-Jin, Shin, Sung Jae, Jeong, Hye-Sook, Yoo, Jung Sik, Shin, EunKyoung, Yeo, Sang-Gu, Chang, Sun-Young, Ko, Hyun-Jeong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6830241/
https://www.ncbi.nlm.nih.gov/pubmed/31736965
http://dx.doi.org/10.3389/fimmu.2019.02542