Opposite Effects of Moderate and Extreme Cx43 Deficiency in Conditional Cx43-Deficient Mice on Angiotensin II-Induced Cardiac Fibrosis

Connexin 43 (Cx43) is essential for cardiac electrical coupling, but its effects on myocardial fibrosis is controversial. Here, we analyzed the role of Cx43 in myocardial fibrosis caused by angiotensin II (AngII) using Cx43(fl/fl) and Cx43(Cre-ER(T)/fl) inducible knock-out (Cx43 content: 50%) mice t...

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Detalles Bibliográficos
Autores principales: Valls-Lacalle, Laura, Negre-Pujol, Corall, Rodríguez, Cristina, Varona, Saray, Valera-Cañellas, Antoni, Consegal, Marta, Martínez-González, Jose, Rodríguez-Sinovas, Antonio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6830333/
https://www.ncbi.nlm.nih.gov/pubmed/31652649
http://dx.doi.org/10.3390/cells8101299

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6830333/
https://www.ncbi.nlm.nih.gov/pubmed/31652649
http://dx.doi.org/10.3390/cells8101299

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