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The Oncogenic Signaling Pathways in BRAF-Mutant Melanoma Cells Are Modulated by Naphthalene Diimide-Like G-Quadruplex Ligands

Melanoma is the most aggressive and deadly type of skin cancer. Despite the advent of targeted therapies directed against specific oncogene mutations, melanoma remains a tumor that is very difficult to treat, and ultimately remains incurable. In the past two decades, stabilization of the non-canonic...

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Detalles Bibliográficos
Autores principales: Recagni, Marta, Tassinari, Martina, Doria, Filippo, Cimino-Reale, Graziella, Zaffaroni, Nadia, Freccero, Mauro, Folini, Marco, Richter, Sara N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6830342/
https://www.ncbi.nlm.nih.gov/pubmed/31635389
http://dx.doi.org/10.3390/cells8101274