Estimating Lifetime Benefits Associated with Immuno-Oncology Therapies: Challenges and Approaches for Overall Survival Extrapolations

BACKGROUND: Standard parametric survival models are commonly used to estimate long-term survival in oncology health technology assessments; however, they can inadequately represent the complex pattern of hazard functions or underlying mechanism of action (MoA) of immuno-oncology (IO) treatments. OBJ...

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Detalles Bibliográficos
Autores principales: Ouwens, Mario J. N. M., Mukhopadhyay, Pralay, Zhang, Yiduo, Huang, Min, Latimer, Nicholas, Briggs, Andrew
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2019
Materias:
Original Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6830404/
https://www.ncbi.nlm.nih.gov/pubmed/31102143
http://dx.doi.org/10.1007/s40273-019-00806-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6830404/
https://www.ncbi.nlm.nih.gov/pubmed/31102143
http://dx.doi.org/10.1007/s40273-019-00806-4

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