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Estimating Lifetime Benefits Associated with Immuno-Oncology Therapies: Challenges and Approaches for Overall Survival Extrapolations
BACKGROUND: Standard parametric survival models are commonly used to estimate long-term survival in oncology health technology assessments; however, they can inadequately represent the complex pattern of hazard functions or underlying mechanism of action (MoA) of immuno-oncology (IO) treatments. OBJ...
Autores principales: | Ouwens, Mario J. N. M., Mukhopadhyay, Pralay, Zhang, Yiduo, Huang, Min, Latimer, Nicholas, Briggs, Andrew |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer International Publishing
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6830404/ https://www.ncbi.nlm.nih.gov/pubmed/31102143 http://dx.doi.org/10.1007/s40273-019-00806-4 |
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