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Diagnostic biomarkers for adult haemophagocytic lymphohistiocytosis in critically ill patients (HEMICU): a prospective observational study protocol

INTRODUCTION: Haemophagocytic lymphohistiocytosis (HLH) in adults is characterised by toxic immune activation and a sepsis-like syndrome, leading to high numbers of undiagnosed cases and mortality rates of up to 68%. Early diagnosis and specific immune suppressive treatment are mandatory to avoid fa...

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Detalles Bibliográficos
Autores principales: Lachmann, Gunnar, Knaak, Cornelia, von Haefen, Clarissa, Paeschke, Nadine, Meisel, Christian, Nyvlt, Peter, Schuster, Friederike S, Piper, Sophie K, Kruppa, Jochen, Vorderwülbecke, Gerald, Balzer, Felix, La Rosée, Paul, Schenk, Thomas, Unterwalder, Nadine, Kölsch, Uwe, Lachmann, Nils, Akyüz, Levent, Brunkhorst, Frank M, Volk, Hans-Dieter, Keh, Didier, Spies, Claudia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6830715/
https://www.ncbi.nlm.nih.gov/pubmed/31666276
http://dx.doi.org/10.1136/bmjopen-2019-032695