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Diagnostic biomarkers for adult haemophagocytic lymphohistiocytosis in critically ill patients (HEMICU): a prospective observational study protocol
INTRODUCTION: Haemophagocytic lymphohistiocytosis (HLH) in adults is characterised by toxic immune activation and a sepsis-like syndrome, leading to high numbers of undiagnosed cases and mortality rates of up to 68%. Early diagnosis and specific immune suppressive treatment are mandatory to avoid fa...
Autores principales: | Lachmann, Gunnar, Knaak, Cornelia, von Haefen, Clarissa, Paeschke, Nadine, Meisel, Christian, Nyvlt, Peter, Schuster, Friederike S, Piper, Sophie K, Kruppa, Jochen, Vorderwülbecke, Gerald, Balzer, Felix, La Rosée, Paul, Schenk, Thomas, Unterwalder, Nadine, Kölsch, Uwe, Lachmann, Nils, Akyüz, Levent, Brunkhorst, Frank M, Volk, Hans-Dieter, Keh, Didier, Spies, Claudia |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BMJ Publishing Group
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6830715/ https://www.ncbi.nlm.nih.gov/pubmed/31666276 http://dx.doi.org/10.1136/bmjopen-2019-032695 |
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