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The NLRP3 inflammasome mediates DSS-induced intestinal inflammation in Nod2 knockout mice

Crohn’s disease (CD) is a chronic disorder of the gastrointestinal tract characterized by inflammation and intestinal epithelial injury. Loss of function mutations in the intracellular bacterial sensor NOD2 are major risk factors for the development of CD. In the absence of robust bacterial recognit...

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Detalles Bibliográficos
Autores principales: Umiker, Benjamin, Lee, Hyun-Hee, Cope, Julia, Ajami, Nadim J., Laine, Jean-Philippe, Fregeau, Christine, Ferguson, Heidi, Alves, Stephen E, Sciammetta, Nunzio, Kleinschek, Melanie, Salmon, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6830860/
https://www.ncbi.nlm.nih.gov/pubmed/30774010
http://dx.doi.org/10.1177/1753425919826367