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The NLRP3 inflammasome mediates DSS-induced intestinal inflammation in Nod2 knockout mice
Crohn’s disease (CD) is a chronic disorder of the gastrointestinal tract characterized by inflammation and intestinal epithelial injury. Loss of function mutations in the intracellular bacterial sensor NOD2 are major risk factors for the development of CD. In the absence of robust bacterial recognit...
Autores principales: | Umiker, Benjamin, Lee, Hyun-Hee, Cope, Julia, Ajami, Nadim J., Laine, Jean-Philippe, Fregeau, Christine, Ferguson, Heidi, Alves, Stephen E, Sciammetta, Nunzio, Kleinschek, Melanie, Salmon, Michael |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
SAGE Publications
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6830860/ https://www.ncbi.nlm.nih.gov/pubmed/30774010 http://dx.doi.org/10.1177/1753425919826367 |
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