The synthetic glycolipid-based TLR4 antagonist FP7 negatively regulates in vitro and in vivo haematopoietic and non-haematopoietic vascular TLR4 signalling

TLRs, including TLR4, have been shown to play a crucial role in cardiovascular inflammatory-based diseases. The main goal of this study was to determine the potential of FP7, a synthetic glycolipid active as a TLR4 antagonist, to modulate haematopoietic and non-haematopoietic vascular TLR4 pro-infla...

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Detalles Bibliográficos
Autores principales: Palmer, Charys, Peri, Francesco, Neumann, Frank, Ahmad, Feroz, Leake, David S., Pirianov, Grisha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2018
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6830872/
https://www.ncbi.nlm.nih.gov/pubmed/30208782
http://dx.doi.org/10.1177/1753425918798904

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6830872/
https://www.ncbi.nlm.nih.gov/pubmed/30208782
http://dx.doi.org/10.1177/1753425918798904

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