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Matrine induces apoptosis via targeting CCR7 and enhances the effect of anticancer drugs in non-small cell lung cancer in vitro

This study mainly investigated the effects of matrine on cell apoptosis and the effects of anticancer drugs in non-small cell lung cancer (NSCLC) cell lines (A549 and LK2 cells). The results showed that matrine (≥10 μM) caused a significant inhibition on cell viability and 10 and 100 μM matrine indu...

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Detalles Bibliográficos
Autores principales: Pu, Jiangtao, Tang, Xiaojun, Zhuang, Xiang, Hu, Zhi, He, Kaiming, Wu, Yunfei, Dai, Tianyang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6830874/
https://www.ncbi.nlm.nih.gov/pubmed/30236029
http://dx.doi.org/10.1177/1753425918800555