Cargando…

Matrine induces apoptosis via targeting CCR7 and enhances the effect of anticancer drugs in non-small cell lung cancer in vitro

This study mainly investigated the effects of matrine on cell apoptosis and the effects of anticancer drugs in non-small cell lung cancer (NSCLC) cell lines (A549 and LK2 cells). The results showed that matrine (≥10 μM) caused a significant inhibition on cell viability and 10 and 100 μM matrine indu...

Descripción completa

Detalles Bibliográficos
Autores principales:	Pu, Jiangtao, Tang, Xiaojun, Zhuang, Xiang, Hu, Zhi, He, Kaiming, Wu, Yunfei, Dai, Tianyang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	SAGE Publications 2018
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6830874/ https://www.ncbi.nlm.nih.gov/pubmed/30236029 http://dx.doi.org/10.1177/1753425918800555

Ejemplares similares

Matrine alleviates lipopolysaccharide-induced intestinal inflammation and oxidative stress via CCR7 signal
por: Wu, Guojun, et al.
Publicado: (2017)

Retraction: Matrine alleviates lipopolysaccharide-induced intestinal inflammation and oxidative stress via CCR7 signal
por: Wu, Guojun, et al.
Publicado: (2023)

Effect of matrine combined with cisplatin on the expression of XIAP in human rhabdomyosarcoma RD cells
por: Li, Li, et al.
Publicado: (2016)

Research Progress of Natural Matrine Compounds and Synthetic Matrine Derivatives
por: Li, Jinlei, et al.
Publicado: (2023)

Effects of matrine on the proliferation and apoptosis of vincristine-resistant retinoblastoma cells
por: Zhao, Bowen, et al.
Publicado: (2020)

Research Advances on Matrine
por: Sun, Xiao-Ying, et al.
Publicado: (2022)

Synthesis, characterization and in vitro biological evaluation of two matrine derivatives
por: Cheng, Xingan, et al.
Publicado: (2018)

Matrine Induces Apoptosis in Human Acute Myeloid Leukemia Cells via the Mitochondrial Pathway and Akt Inactivation
por: Zhang, Shenghui, et al.
Publicado: (2012)

Molecular Mechanism of Matrine from Sophora alopecuroides in the Reversing Effect of Multi-Anticancer Drug Resistance in K562/ADR Cells
por: Chen, Zhi, et al.
Publicado: (2019)

Blocking Autophagic Flux Enhances Matrine-Induced Apoptosis in Human Hepatoma Cells
por: Wang, Li, et al.
Publicado: (2013)

Matrine treatment reduces retinal ganglion cell apoptosis in experimental optic neuritis
por: Kang, Jian, et al.
Publicado: (2021)

Matrine attenuates focal cerebral ischemic injury by improving antioxidant activity and inhibiting apoptosis in mice
por: ZHAO, PENG, et al.
Publicado: (2015)

Simultaneous Determination of Matrine and Tinidazole in Compound Lotion by RH-HPLC Method
por: Yin, Zhikui, et al.
Publicado: (2013)

Combining Oxymatrine or Matrine with Lamivudine Increased Its Antireplication Effect against the Hepatitis B Virus In Vitro
por: Ma, Zhi-Jie, et al.
Publicado: (2013)

The combined usage of Matrine and Osthole inhibited endoplasmic reticulum apoptosis induced by PCV2
por: Xu, Yinlan, et al.
Publicado: (2020)

Sedative Effect of Sophora flavescens and Matrine
por: Lee, Hyun-ju, et al.
Publicado: (2017)

Matrin3: Disorder and ALS Pathogenesis
por: Salem, Ahmed, et al.
Publicado: (2022)

Research progress on the pharmacological effects of matrine
por: Sun, Yanan, et al.
Publicado: (2022)

Regulation of CCR7-dependent cell migration through CCR7 homodimer formation
por: Kobayashi, Daichi, et al.
Publicado: (2017)

Systematic Assessment of Chemokine Signaling at Chemokine Receptors CCR4, CCR7 and CCR10
por: Lim, Herman D., et al.
Publicado: (2021)

Identification of RHEX as a novel biomarker related to progression and immunity of non-small cell lung carcinoma
por: Xu, Tao, et al.
Publicado: (2021)

Matrine Induction of ROS Mediated Apoptosis in Human ALL B-lymphocytes Via Mitochondrial Targeting
por: Aghvami, Marjan, et al.
Publicado: (2018)

Matrine exerts anti-breast cancer activity by mediating apoptosis and protective autophagy via the AKT/mTOR pathway in MCF-7 cells
por: Du, Jikun, et al.
Publicado: (2020)

CCL21/CCR7 Prevents Apoptosis via the ERK Pathway in Human Non-Small Cell Lung Cancer Cells
por: Xu, Ying, et al.
Publicado: (2012)

Probucol-induced hERG Channel Reduction can be Rescued by Matrine and Oxymatrine in vitro
por: Shi, Yuan-Qi, et al.
Publicado: (2019)

Matrine inhibits itching by lowering the activity of calcium channel
por: Geng, Xiao, et al.
Publicado: (2018)

Matrine Impairs Platelet Function and Thrombosis and Inhibits ROS Production
por: Zhang, Sixuan, et al.
Publicado: (2021)

Matrin 3 Binds and Stabilizes mRNA
por: Salton, Maayan, et al.
Publicado: (2011)

Matrin 3 in neuromuscular disease: physiology and pathophysiology
por: Malik, Ahmed M., et al.
Publicado: (2021)

Effects of matrine in combination with cisplatin on liver cancer
por: Hu, Gaoyu, et al.
Publicado: (2021)

Matrine Promotes Human Myeloid Leukemia Cells Apoptosis Through Warburg Effect Mediated by Hexokinase 2
por: Lin, Guibin, et al.
Publicado: (2019)

Matrine combined with Osthole inhibited the PERK apoptosis of splenic lymphocytes in PCV2-infected mice model
por: Xu, Yinlan, et al.
Publicado: (2023)

CC Chemokines in a Tumor: A Review of Pro-Cancer and Anti-Cancer Properties of Receptors CCR5, CCR6, CCR7, CCR8, CCR9, and CCR10 Ligands
por: Korbecki, Jan, et al.
Publicado: (2020)

Effects of Sophora flavescens aiton and the absorbed bioactive metabolite matrine individually and in combination with 5-fluorouracil on proliferation and apoptosis of gastric cancer cells in nude mice
por: Hu, Huan-Fu, et al.
Publicado: (2022)

Matrine attenuates oxidative stress and cardiomyocyte apoptosis in doxorubicin-induced cardiotoxicity via maintaining AMPKα/UCP2 pathway
por: Hu, Can, et al.
Publicado: (2019)

Anticancer and apoptosis-inducing effects of quercetin in vitro and in vivo
por: Hashemzaei, Mahmoud, et al.
Publicado: (2017)

Synthesis of a Temperature-Sensitive Matrine-Imprinted Polymer and Its Potential Application for the Selective Extraction of Matrine from Radix Sophorae Tonkinensis
por: Jiang, Minjie, et al.
Publicado: (2015)

The Ins and Outs of CCR7 in the Thymus
por: Witt, Colleen M., et al.
Publicado: (2004)

Matrine Activates PTEN to Induce Growth Inhibition and Apoptosis in (V600E)BRAF Harboring Melanoma Cells
por: Jin, Hui, et al.
Publicado: (2013)

Licochalcone H induces the apoptosis of human oral squamous cell carcinoma cells via regulation of matrin 3
por: Nho, Su-Hyun, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_g5smacvg4g8qcc1c3r6mlpnjme