Cargando…

Regulation of dendritic cell function improves survival in experimental sepsis through immune chaperone

Dendritic cells (DCs) are professional Ag-presenting cells that play a critical role in both innate and adaptive immune responses. DCs recognize and respond to bacteria through multiple PRRs, including TLRs. Heat shock protein gp96/grp94 is a master essential chaperone for TLRs in the endoplasmic re...

Descripción completa

Detalles Bibliográficos
Autores principales: Li, Pengfei, Zhao, Ran, Fan, Kevin, Iwanowycz, Stephen, Fan, Hongkuan, Li, Zihai, Liu, Bei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6830886/
https://www.ncbi.nlm.nih.gov/pubmed/31018807
http://dx.doi.org/10.1177/1753425919840423