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Comparison of different lots of endotoxin and evaluation of in vivo potency over time in the experimental human endotoxemia model

The experimental human endotoxemia model is used to study the systemic inflammatory response in vivo. The previously used lot of endotoxin, which was used for over a decade, is no longer approved for human use and a new Good Manufacturing Practices-grade batch has become available. We compared the i...

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Detalles Bibliográficos
Autores principales: Kiers, Dorien, Leijte, Guus P., Gerretsen, Jelle, Zwaag, Jelle, Kox, Matthijs, Pickkers, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6830888/
https://www.ncbi.nlm.nih.gov/pubmed/30782041
http://dx.doi.org/10.1177/1753425918819754