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Comparison of different lots of endotoxin and evaluation of in vivo potency over time in the experimental human endotoxemia model
The experimental human endotoxemia model is used to study the systemic inflammatory response in vivo. The previously used lot of endotoxin, which was used for over a decade, is no longer approved for human use and a new Good Manufacturing Practices-grade batch has become available. We compared the i...
Autores principales: | Kiers, Dorien, Leijte, Guus P., Gerretsen, Jelle, Zwaag, Jelle, Kox, Matthijs, Pickkers, Peter |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
SAGE Publications
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6830888/ https://www.ncbi.nlm.nih.gov/pubmed/30782041 http://dx.doi.org/10.1177/1753425918819754 |
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