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Pyocyanin induces NK92 cell apoptosis via mitochondrial damage and elevated intracellular Ca(2+)

Pseudomonas aeruginosa-derived pigment pyocyanin (PCN) has been proved to induce cell apoptosis mediated by the generation of reactive oxygen species (ROS), which has been studied mainly in epithelial cells and neutrophils. However, we previously found that the PCN-producing strain PA14 induces cell...

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Detalles Bibliográficos
Autores principales: Li, Ting, Huang, Xiaoyuan, Yuan, Zhechen, Wang, Linfang, Chen, Miaobo, Su, Fenfen, Ling, Xiaojing, Piao, Zhenghao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6830894/
https://www.ncbi.nlm.nih.gov/pubmed/30426809
http://dx.doi.org/10.1177/1753425918809860