Disruption of transient receptor potential melastatin 2 decreases elastase release and bacterial clearance in neutrophils

Elastase released by neutrophils is critical for eliminating Gram-negative bacteria. Ca(2+) influx plays a key role in elastase release and bacterial clearance in neutrophils. Transient receptor potential melastatin 2 (TRPM2) is a Ca(2+)-permeable cation channel highly expressed in neutrophils. Here...

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Detalles Bibliográficos
Autores principales: Qian, XiaoWei, Zhao, Hang, Chen, XinZhong, Li, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2018
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6830898/
https://www.ncbi.nlm.nih.gov/pubmed/29495939
http://dx.doi.org/10.1177/1753425918759181

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6830898/
https://www.ncbi.nlm.nih.gov/pubmed/29495939
http://dx.doi.org/10.1177/1753425918759181

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