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Analysis of IL-6 and IL-1β release in cryopreserved pooled human whole blood stimulated with endotoxin

To overcome the lack of availability of fresh human whole blood for pyrogen detection, we explored the feasibility of utilizing cryopreserved pooled human blood to detect the responses of the pro-inflammatory cytokines IL-6 and IL-1β to LPS. Whole blood was obtained from five donors and incubated wi...

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Detalles Bibliográficos
Autores principales: He, Qing, Gao, Hua, Xu, Li-ming, Lu, Yan, Wang, Chong, Rui, Jing, Fan, Hua, Wang, Xiu-ying, Wang, Jun-zhi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6830915/
https://www.ncbi.nlm.nih.gov/pubmed/29793382
http://dx.doi.org/10.1177/1753425918777596