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Endothelin signalling mediates experience-dependent myelination in the CNS

Experience and changes in neuronal activity can alter CNS myelination, but the signalling pathways responsible remain poorly understood. Here we define a pathway in which endothelin, signalling through the G protein-coupled receptor endothelin receptor B and PKC epsilon, regulates the number of myel...

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Detalles Bibliográficos
Autores principales: Swire, Matthew, Kotelevtsev, Yuri, Webb, David J, Lyons, David A, ffrench-Constant, Charles
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6831104/
https://www.ncbi.nlm.nih.gov/pubmed/31657718
http://dx.doi.org/10.7554/eLife.49493