HBX-induced miR-5188 impairs FOXO1 to stimulate β-catenin nuclear translocation and promotes tumor stemness in hepatocellular carcinoma

Cancer stem cells (CSCs) are the key factor in determining cancer recurrence, metastasis, chemoresistance and patient prognosis in hepatocellular carcinoma (HCC). The role of miR-5188 in cancer stemness has never been documented. In this study, we investigated the clinical and biological roles of mi...

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Detalles Bibliográficos
Autores principales: Lin, Xian, Zuo, Shi, Luo, Rongcheng, Li, Yonghao, Yu, Guifang, Zou, Yujiao, Zhou, Yan, Liu, Zhan, Liu, Yiyi, Hu, Yingying, Xie, Yingying, Fang, Weiyi, Liu, Zhen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2019
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6831466/
https://www.ncbi.nlm.nih.gov/pubmed/31695788
http://dx.doi.org/10.7150/thno.37717

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6831466/
https://www.ncbi.nlm.nih.gov/pubmed/31695788
http://dx.doi.org/10.7150/thno.37717

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