The use of micelles to deliver potential hedgehog pathway inhibitor for the treatment of liver fibrosis

Rationale: Hedgehog (Hh) pathway plays an essential role in liver fibrosis by promoting the proliferation of hepatic stellate cells (HSCs) by enhancing their metabolism via yes-associated protein 1 (YAP1). Despite the presence of several inhibitors, Hh signaling cannot be controlled exclusively due...

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Detalles Bibliográficos
Autores principales: Kumar, Virender, Dong, Yuxiang, Kumar, Vinod, Almawash, Saud, Mahato, Ram I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2019
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6831471/
https://www.ncbi.nlm.nih.gov/pubmed/31695785
http://dx.doi.org/10.7150/thno.38913

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6831471/
https://www.ncbi.nlm.nih.gov/pubmed/31695785
http://dx.doi.org/10.7150/thno.38913

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