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Increased circulating peroxiredoxin-4 in sepsis model rats involves secretion from hepatocytes and is mitigated by GYY4137

Circulating peroxiredoxin-4 (Prx4) is suggested as a prognosis marker as well as a regulator of many diseases. We aimed to examine 1) whether Prx4 is secreted from the liver in an animal model of sepsis and 2) effects of GYY4137, a hydrogen sulfide donor molecule, on septic liver injury as well as t...

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Detalles Bibliográficos
Autores principales: Unuma, Kana, Yoshikawa, Ayaka, Aki, Toshihiko, Uemura, Koichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Japanese Society of Toxicologic Pathology 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6831490/
https://www.ncbi.nlm.nih.gov/pubmed/31719759
http://dx.doi.org/10.1293/tox.2019-0030